Can You Take Muscle Relaxers With Blood Thinners

Past Steven Reinberg
HealthDay Reporter

MONDAY, April 14, 2022 (HealthDay News) -- People taking blood thinners to prevent clots in their legs or lungs may put themselves at chance for serious internal bleeding if they besides take mutual painkillers such equally aspirin or ibuprofen, researchers warn.

These over-the-counter painkillers -- called nonsteroidal anti-inflammatory drugs (NSAIDs) -- include such drugs as Advil, Aleve, Bufferin, Excedrin, Motrin and Nuprin, every bit well as aspirin. Patients who use claret thinners such as warfarin, Eliquis, Xarelto or Pradaxa should not take them, the researchers said.

"If you are taking an NSAID while taking an anticoagulant, your take chances of a major bleed is double what information technology would be if y'all weren't taking an NSAID," said lead researcher Dr. Bruce Davidson. He's with the sectionalization of pulmonary and disquisitional care medicine at the University of Washington School of Medicine in Seattle.

One-quarter of these major bleeds happen within eight days of taking an NSAID, Davidson said. "It'south not like you have to be taking them for weeks or months. Some bleeds happen with a single dose," he said.

The risk of bleeding might exist even greater for people with an irregular heartbeat, chosen atrial fibrillation, who take a blood thinner and use an NSAID, Davidson said.

"The message for people is if yous're taking a blood thinner, do not take an NSAID -- merely don't take i," Davidson said.

"If y'all accept a headache or aching muscles or joints, take generic Tylenol [acetaminophen]. Don't take NSAIDs for casual apply," he added.

The report, published online April 14 in JAMA Internal Medicine, said the bleeding is oft minor but can be fatal in some cases.

Information technology's known that aspirin use by patients on anticoagulant therapy doubles the risk of bleeding, said Dr. Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and spokesman for the American Heart Clan.

But whether NSAIDs such as Advil or Motrin are associated with increased gamble of haemorrhage among patients receiving anticoagulant therapy wasn't clear, Fonarow said. Some studies showed raised risk with drugs like Coumadin (warfarin), Eliquis (apixaban), Xarelto (rivaroxaban) or Pradaxa (dabigatran), while others didn't.

Patients should consult their doctor before combining these medications, he advised.

"NSAID or aspirin therapy should exist used only with caution and only if no similarly constructive and safer culling treatment is available. Use of Tylenol may be more than advisable for people with headache or muscle aches while receiving anticoagulation therapy," Fonarow said.

For the written report, Davidson's team analyzed data from the worldwide EINSTEIN deep vein thrombosis and pulmonary embolism studies, which included over 8,000 patients. The trials compared two blood thinners -- Xarelto and warfarin -- to see which was better at preventing blood clots in the legs and lungs.

Drugs that forestall clotting e'er carry the additional risk of internal bleeding, which tin become serious and life-threatening, experts say.

Davidson's group also looked at whether taking NSAIDs with these blood thinners might increase the hazard for bleeding. They institute it did.

He said that, according to the study, the absolute take chances for a major haemorrhage episode for a patient taking aspirin and a blood thinner was nearly double that of a patient not on aspirin. For patients taking another form of NSAID plus a blood thinner, at that place was triple the adventure compared to those taking the claret thinner alone, Davidson said.

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However, the association institute in the study does not prove a cause-and-effect link.

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References

SOURCES: Bruce Davidson, One thousand.D., 1000.P.H., partitioning of pulmonary and critical care medicine, Academy of Washington School of Medicine, Seattle; Gregg Fonarow, M.D., professor, cardiology, University of California, Los Angeles, and spokesman, American Heart Association; April fourteen, 2014, JAMA Internal Medicine, online

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Source: https://www.medicinenet.com/script/main/art.asp?articlekey=177914

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